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afya
Wilms tumour
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> Nephroblastoma one of common childhood malignancy usually <5 (average 3yr) features abdo mass flank pain painless haematuria anorexia fever 95% unilat 20% mets (usually lung) on presentation associations Beckwith-Wiederman WAGR syndrome - aniridia, GU malformation, mental retardation hemihypertrophy 1/3 have mutation in WT1 gene on chromosome 11 Mx Nephrectomy Chemo Radio if advanced good prognosis - 80% cure
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