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afya
SLE
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> Multisystem autoimmune disorder Early adulthood, women, afro-carribean General features - fatigue, fever, mouth ulcers, lymphadenopathy Also Skin ... Musculoskeletal - arthralgia, non-erosive arthritis CVS - Myocarditis Resp - pleurisy and fibrosing alveolitis Renal - proteinuria, glomerulonephritis (most commonly diffuse proliferative GN) Neuropsych - anxiety/depression, psychosis, seizures ''Skin '' malar (Butterfly) rash (spares nasolabial folds) Discoid rash - scaly erythematous well demarcated in sun exposed areas (may progress to being pigmented and hyperkeratotic and then atrophic photosensitivity Raynaud livedo reticularis non-scarring alopecia ESR raised but CRP may be normal
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