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afya SLE

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20160425222427 Ben  
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Multisystem autoimmune disorder
Early adulthood, women, afro-carribean

General features - fatigue, fever, mouth ulcers, lymphadenopathy
Also Skin ... 
Musculoskeletal - arthralgia, non-erosive arthritis
CVS - Myocarditis
Resp - pleurisy and fibrosing alveolitis
Renal - proteinuria, glomerulonephritis (most commonly diffuse proliferative GN)
Neuropsych - anxiety/depression, psychosis, seizures

''Skin ''
malar (Butterfly) rash (spares nasolabial folds)
Discoid rash - scaly erythematous well demarcated in sun exposed areas (may progress to being pigmented and hyperkeratotic and then atrophic
photosensitivity
Raynaud
livedo reticularis
non-scarring alopecia

ESR raised but CRP may be normal