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afya
SJS
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> Stevens-Johnson (<10%) and toxic epidermal necrolysis (>30%) epidermal detachment often drug induced - esp sulphonamides, maybe with infection ??target lesions but also at least 2 mucosal sites of mucocutaneous necrosis and fever Mx stop precipitant beware electrolytes / sepsis / multisystem failure mortality 5-12% SJS, >30% TEN ''Features'' rash is typically maculopapular with target lesions being characteristic. May develop into vesicles or bullae mucosal involvement systemic symptoms: fever, arthralgia ''Causes'' idiopathic bacteria: Mycoplasma, Streptococcus viruses: herpes simplex virus, Orf drugs: penicillin, sulphonamides, carbamazepine, allopurinol, NSAIDs, oral contraceptive pill connective tissue disease e.g. SLE sarcoidosis malignancy
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Erythema, DermEmergencies