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Stevens-Johnson (<10%) and toxic epidermal necrolysis (>30%) epidermal detachment
often drug induced - esp sulphonamides, maybe with infection

??target lesions but also  at least 2 mucosal sites of mucocutaneous necrosis and fever

Mx
stop precipitant
beware electrolytes / sepsis / multisystem failure
mortality 5-12% SJS, >30% TEN

''Features''
    rash is typically maculopapular with target lesions being characteristic. May develop into vesicles or bullae
    mucosal involvement
    systemic symptoms: fever, arthralgia

''Causes''
    idiopathic
    bacteria: Mycoplasma, Streptococcus
    viruses: herpes simplex virus, Orf
    drugs: penicillin, sulphonamides, carbamazepine, allopurinol, NSAIDs, oral contraceptive pill
    connective tissue disease e.g. SLE
    sarcoidosis
    malignancy