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Primary Hyperaldosteronism
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<<forEachTiddler where 'tiddler.tags.contains(context.inTiddler.title)' sortBy tiddler.title ascending write '"*[["+tiddler.title+"]]\n"'>> <<tiddler AutoRefresh with: force>> Aldosterone retains water and sodium (renal tubule) So Na inc, BP inc, K dec, alkalosis ''Causes'' Adrenal adenoma - Conn's Bilateral Idiopathic Adrenal Hyperplasia - 70% Adrenal carcinoma - rare ''Features'' hypertension hypokalaemia (e.g. muscle weakness) alkalosis ''Investigations'' high serum aldosterone low serum renin high-resolution CT abdomen adrenal vein sampling ''Management'' adrenal adenoma: surgery bilateral adrenocortical hyperplasia: aldosterone antagonist e.g. spironolactone
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