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afya Primary Hyperaldosteronism

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20160425222500 Ben  
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Aldosterone retains water and sodium (renal tubule)
So Na inc, BP inc, K dec, alkalosis

''Causes''
Adrenal adenoma - Conn's
Bilateral Idiopathic Adrenal Hyperplasia - 70%
Adrenal carcinoma - rare

''Features''
hypertension
hypokalaemia (e.g. muscle weakness)
alkalosis

''Investigations''
high serum aldosterone
low serum renin
high-resolution CT abdomen
adrenal vein sampling

''Management''
adrenal adenoma: surgery
bilateral adrenocortical hyperplasia: aldosterone antagonist e.g. spironolactone