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afya
Pre-diabetes
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> 1 in 7 adults in UK Many will progress to T2DM so inc risk both micro and macro vascular Term pre-diabetes is best understood by public assess risk in all over 40, over 20 if chinese, south-asian or any condition inc risk and do blood test ''Fasting glc 5.5-6.9, HbA1C 43-47 (6-6.4%)'' suggests high risk ''Mx'' lifestyle modification - wt loss, exercize, diet change yearly repeat bloods consider metformin (start if lifestyle change occurs but still worsening of HbA1C) ''2 types'' ''Impaired Fasting Glucose'' due to hepatic insulin resistance (less serious) fasting glucose 6.1-7.0 needs OGTT ''Impaired Glucose Tolerance'' due to to muscle insulin resistance more likely to progress and develop CVS disease fasting glc <7 with 2hr post load 7.8-11.1
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Diabetes