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afya
Huntingdon's
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<<forEachTiddler where 'tiddler.tags.contains(context.inTiddler.title)' sortBy tiddler.title ascending write '"*[["+tiddler.title+"]]\n"'>> <<tiddler AutoRefresh with: force>> inherited neurodegenerative condition. progressive and incurable condition that typically results in death 20 years after the initial symptoms develop. ''Genetics'' autosomal dominant trinucleotide repeat disorder: repeat expansion of CAG results in degeneration of cholinergic and GABAergic neurons in the striatum of the basal ganglia due to defect in huntingtin gene on chromosome 4 ''Features typical develop after 35 years of age'' chorea personality changes (e.g. irritability, apathy, depression) and intellectual impairment dystonia saccadic eye movements
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Neurology