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Cervical screening
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> abnormal in 5% |Borderline or mild dyskaryosis|test original sample for high risk HPV (16,18,33) - -ve routine recall, +ve colposcopy| |Moderate dyskaryosis (CIN II)|Refer for colposcopy| |Severe dyskaryosis (CIN III)|Refer for colposcopy| |Inadequate|Repeat smear - if persistent (3), assessment by colposcopy| estimated to prevent 1,000-4,000 deaths per year. cervical adenocarcinomas, (15%) are frequently undetected by screening ''Who is screened and how often?'' In England .... 25-49 years: 3-yearly screening 50-64 years: 5-yearly screening In Scotland 20-60 every 3yr traditional Papanicolaou (Pap) smears - less done now liquid-based cytology (LBC) - brush head in preserving fluid - reduces rate of inadequate and inc sens and spec ?do mid cycle - limited evidence
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GynaeCancer