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abnormal in 5% 

|Borderline or mild dyskaryosis|test original sample for high risk HPV (16,18,33) - -ve routine recall, +ve colposcopy|
|Moderate dyskaryosis (CIN II)|Refer for colposcopy|
|Severe dyskaryosis (CIN III)|Refer for colposcopy|
|Inadequate|Repeat smear - if persistent (3), assessment by colposcopy|

estimated to prevent 1,000-4,000 deaths per year. 
cervical adenocarcinomas, (15%) are frequently undetected by screening

''Who is screened and how often?''
In England .... 
    25-49 years: 3-yearly screening
    50-64 years: 5-yearly screening
In Scotland 20-60 every 3yr

traditional Papanicolaou (Pap) smears - less done now
liquid-based cytology (LBC) - brush head in preserving fluid - reduces rate of inadequate and inc sens and spec
?do mid cycle - limited evidence