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afya
CLL
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<<forEachTiddler where 'tiddler.tags.contains(context.inTiddler.title)' sortBy tiddler.title ascending write '"*[["+tiddler.title+"]]\n"'>> <<tiddler AutoRefresh with: force>> caused by a monoclonal proliferation of well-differentiated lymphocytes which are almost always B-cells (99%) ''Features'' often none constitutional: anorexia, weight loss bleeding, infections lymphadenopathy more marked than CML ''Complications'' hypogammaglobulinaemia leading to recurrent infections warm autoimmune haemolytic anaemia in 10-15% of patients transformation to high-grade lymphoma (Richter's transformation) ''Investigations'' blood film: smudge cells immunophenotyping
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Haematology