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afya
Angiotensin II receptor blockers
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<<forEachTiddler where 'tiddler.tags.contains(context.inTiddler.title)' sortBy tiddler.title ascending write '"*[["+tiddler.title+"]]\n"'>> <<tiddler AutoRefresh with: force>> NICE 'Offer people aged under 55 years an ACE inhibitor or a low-cost ARB. If an ACE inhibitor is prescribed and is not tolerated (for example, because of cough), offer a low-cost ARB.' Up to 15% of patients who are started on an ACE inhibitor develop a dry cough. ARB used when ACE not tolerated usually due to cough. ''Examples'' candesartan losartan irbesartan use with caution in patients with renovascular disease. ''Side-effects'' include hypotension and hyperkalaemia. ''Mechanism'' block effects of angiotensin II at the AT1 receptor Evidence base shown to reduce progression of renal disease in patients with diabetic nephropathy evidence base that losartan reduces CVA and IHD mortality in hypertensive patients
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