Not using an installer
Many experienced Python developers prefer to handle installing packages on their own. If you don't like pip you can get the latest tarballs from http://pypi.python.org/pypi/tiddlyweb and http://pypi.python.org/pypi/tiddlywebwiki and process
setup.py in whatever way you deem reasonable.
Install or run from source
git clone git://github.com/tiddlyweb/tiddlyweb.git cd tiddlyweb
(or a clone of your own fork, if you work that way)
README file you will find there to see the other modules you need to install.