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oncological emergency
affects up to 5% of cancer patients
Mostly Extradural compression accounts for the majority of cases, usually vertebral body metastases
more common with lung, breast and prostate cancer
''Features''
back pain - the earliest and most common symptom - may be worse on lying down and coughing
lower limb weakness
sensory changes: sensory loss and numbness
neurological signs depend on the level of the lesion...
>L1 UMN legs and sensory level usually
<L1 LMN legs and perianal numbness
Tendon reflexes tend to be increased below the level of the lesion and absent at the level of the lesion
''Management''
high-dose oral dexamethasone
urgent oncological assessment for consideration of radiotherapy or surgery