<<forEachTiddler where 'tiddler.tags.contains(context.inTiddler.title)'
sortBy
tiddler.title
ascending
write '"*[["+tiddler.title+"]]\n"'>>
<<tiddler AutoRefresh with: force>>
used in management of seizures.
''Mechanism of action''
sodium channel blocker, decreasing the sodium influx into neurons which in turn decreases excitability
''Adverse effects''
''Acute''
initially: dizziness, diplopia, nystagmus, slurred speech, ataxia
later: confusion, seizures
''Chronic''
common: gingival hyperplasia (secondary to increased expression of platelet derived growth factor, PDGF), hirsutism, coarsening of facial features, drowsiness
megaloblastic anaemia (secondary to altered folate metabolism)
peripheral neuropathy
enhanced vitamin D metabolism causing osteomalacia
lymphadenopathy
dyskinesia
''Idiosyncratic''
fever
rashes, including severe reactions such as toxic epidermal necrolysis
hepatitis
Dupuytren's contracture
aplastic anaemia
drug-induced lupus
''Teratogenic''
associated with cleft palate and congenital heart disease