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afya Pertussis

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20160425222506 Ben  
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caused by gram negative - Bordetella pertussis
incubation 10-14 days
children in UK vaccinated - 2,3,4/12 and 4 yrs
1000 cases in UK /yr

''Features''
2-3 days coryza then
coughing bout - worse at night and after feeds, may end with vomiting and central cyanosis
inspiratory whoop (uncommon in infants - forced inspiration against closed glottis)
subconjunctival haemorrhage and anoxia leading to syncope and seizures - from persistent coughing
Sx may last 10-14 WEEKS - more severe in infants
lymphocytosis

''Diagnosis''
nasal swab - takes days to weeks 
PCR and serology are starting to be used

''Mx''
oral erythro to eradicate organism and reduce spread, doesn't change course of illness

''Complications''
Pneumonia
bronchiectasis
seizures