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afya Hypotonia

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20160425222513 Ben  
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floppiness, 
may be central in origin or related to nerve and muscle problems. 
An acutely ill child (e.g. septicaemic) may be hypotonic on examination. 
Hypotonia associated with encephalopathy in the newborn period is most likely caused by hypoxic ischaemic encephalopathy

''Central causes''
Down's syndrome
Prader-Willi syndrome
hypothyroidism
cerebral palsy (hypotonia may precede the development of spasticity)

''Neurological and muscular problems'' 
spinal muscular atrophy
spina bifida
Guillain-Barre syndrome
myasthenia gravis
muscular dystrophy
myotonic dystrophy