<<forEachTiddler  where 'tiddler.tags.contains(context.inTiddler.title)'
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<<tiddler AutoRefresh with: force>>

Gell and Coombs classification

''Type I - Anaphylactic''
    antigen reacts with IgE bound to mast cells
    anaphylaxis, atopy (e.g. asthma, eczema and hayfever)

''Type II - Cell bound''
    IgG or IgM binds to antigen on cell surface
    autoimmune haemolytic anaemia, ITP, Goodpasture's, pernicious anemia, acute hemolytic transfusion reactions, rheumatic fever, bullous pemphigoid, pemphigus vulgaris

''Type III - Immune complex''
    free antigen and antibody (IgG, IgA) combine
    serum sickness, systemic lupus erythematosus, post-streptococcal glomerulonephritis, extrinsic allergic alveolitis (especially acute phase)

''Type IV - Delayed hypersensitivity''
    T cell mediated
    tuberculosis, tuberculin skin reaction, graft versus host disease, allergic contact dermatitis, scabies, extrinsic allergic alveolitis (especially chronic phase), multiple sclerosis, Guillain-Barre syndrome

''Type V'' (new)
    antibodies that recognise and bind to the cell surface receptors, either stimulating them or blocking ligand binding
    Graves' disease, myasthenia gravis