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afya Hereditary haemorrhagic telangiectasia

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20160425222516 Ben  
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Also known as Osler-Weber-Rendu syndrome,
autosomal dominant condition 
characterised by multiple telangiectasia over skin and mucous membranes. 
20% occur spontaneously without prior family history.

''4 diagnostic criteria'' if 2 then possible diagnosis of HHT, if 3+ definite diagnosis of HHT:
    epistaxis : spontaneous, recurrent nosebleeds
    telangiectases: multiple at characteristic sites (lips, oral cavity, fingers, nose)
    visceral lesions: for example gastrointestinal telangiectasia (with or without bleeding), pulmonary arteriovenous malformations (AVM), hepatic AVM, cerebral AVM, spinal AVM
    family history: a first-degree relative with HHT