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afya Graves Disease

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20160425222531 Ben  
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Most common cause of thyrotoxicosis
Women aged 30-50

''Features''
Typical thyrotoxicosis
Specific - 
eye signs - only 30% pts - exophthalmos, ophthalmoplegia
pretibial myxoedema
thyroid acropachy (clubbing (subperiosteal bone formation) and swollen digits

''Autoantibodies''
antiTSH receptor stimulating antibodies - 90%
anti-thyroid peroxidase antibodies - 50%