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20160425222537 Ben  
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''levonorgestrel''
take asap (certainly by 72hrs) - 84% effective
1.5g stat
action - effects ovulation and inhibits implantation - not fully understood
well tolerate - may upset cycle
1% women vomit - if within 2hr - repeat
can be used again in same cycle
avoid in liver disease / porphyria
if taking enzyme inducing drugs then double dose

''Ulipristal''
progesterone receptor modulator - ? inhibits ovulation
30mg asap (not more than 120hrs since UPSI)
don't use with levonorgestrel
may effect use of COCP and POP
beware in severe asthmatics on oral steroids or liver disease
only use once in one cycle
avoid breast feeding for 1/52
don't use if on enzyme inducers

''IUD''
Insert within 5 days of UPSI (or up to 5 days post ovulation)
Inhibits fertilization or implantation
If high risk STI - also give Abs
99% effective
keep in till next period or for ongoing contraception

Note IUD should be offered first line
if on gastric acid Rx - reduce efficacy of oral EC

liver enzyme inducers of importance ...
    antiepileptic - Carbamazepine, Eslicarbazepine, Oxcarbazepine, Phenytoin, Phenobarbital
    antibiotics - Rifabutin, Rifampicin
    antiretroviral
        protease inhibitors - Ritonavir, Ritonavir-boosted atazanavir, darunavir, fosamprenavir, lopinavir,
        non-nucleoside reverse transcriptase inhibitors - Efavirenz, Nevirapine
    Herbal - St Johns Wort (3)