<<forEachTiddler where 'tiddler.tags.contains(context.inTiddler.title)' sortBy tiddler.title ascending write '"*[["+tiddler.title+"]]\n"'>> <<tiddler AutoRefresh with: force>> ''Lentigo'' - (lentigines) hyperplasia of melanocytes (more - so same colour in sun) - linear in spread (spread to cell layer directly above basement membrane) cf - Freckles (ephelis) have normal number of melanocytes but inc melanin so get darker in the sun or - Moles (melanocytic naevi) have nests of multi-layer melanocytes may be .... simple or juvenile - from birth or childhood, not sun induced solar or senile - develop with age due to sun exposure - may be irregular mucosal lentigo maligna - melanoma in situ which progresses slowly, related to sun exposure and therefore age, 2-5% evolve to LMM lentigo maligna melanoma - as LM develops bumpy surface (vertical invasion) - treat as invasive melanoma Other DD Cutaneous horn - horn like projections of keratin usually on elevated base - may develop from - AK, SCC, seb keratosis, warts Sebaceous hyperplasia - multiple, greasy, may have central depression Seborrhoeic Dermatitis -redness scaling, usually itch, common, occurs where sebaceous glands are active, may co-exist with AK Intradermal naevus -pigmentation varies but rarely translucent like BCC. Hairs from lesion suggest naevus Atypical naevus - larger, variegated, asymmetric, irregular outline Compound naevus - combined junctional and dermal - dark, dome, smooth Seborrhoeic keratosis (BCP) - stuck on, elderly, may itch elderly, colour varies, may have horn Malignant Melanoma - vary ..... flat, nodular, ulcerative, pigmented or not Discoid lupus - sun exposed areas, well demarcated, erythematous, hyperkeratotic plaques with follicular plugging. leaves atrophic scar Discoid eczema - clearly demarcated, itchy, scaly, erthematous plaques - coalescing vesicles and papules - maybe exudative / crusty, heal with scarring