<<forEachTiddler where 'tiddler.tags.contains(context.inTiddler.title)'
sortBy
tiddler.title
ascending
write '"*[["+tiddler.title+"]]\n"'>>
<<tiddler AutoRefresh with: force>>
oral anticoagulant - direct thrombin inhibitor.
developed as an alternative to warfarin - not require regular monitoring.
prophylaxis of venous thromboembolism following hip or knee replacement surgery.
prevention of stroke in non-valvular AF with one of ...
previous stroke, transient ischaemic attack or systemic embolism
left ventricular ejection fraction below 40%
symptomatic heart failure of New York Heart Association (NYHA) class 2 or above
age 75 years or older
age 65 years or older with one of the following: diabetes mellitus, coronary artery disease or hypertension
''Adverse effects''
haemorrhage
reduce in CKD (avoid if creatinine clearance is < 30 ml/min)
Note ...
RE-ALIGN study - higher bleeding and thrombotic events with recent mechanical heart valve replacement - dabigatran cf warfarin (so use warfarin)
ie CI in pts with mechanical heart valves