<<forEachTiddler  where 'tiddler.tags.contains(context.inTiddler.title)'
sortBy 
        tiddler.title
    ascending 
write '"*[["+tiddler.title+"]]\n"'>>
<<tiddler AutoRefresh with: force>>
''Presentation''
late adolescence or early adulthood
non-specific symptoms eg weight loss / lethargy
diarrhoea - most prominent symptom in adults. (Crohn's colitis may cause bloody diarrhoea)
abdominal pain: most prominent symptom in children
perianal disease: e.g. Skin tags or ulcers
extra-intestinal features esp with colitis or perianal disease

effects terminal ileum and colon commonly but may effect any bit of bowel

''Induce Remission ''
Glucocorticoids (oral, topical, IV) or Budesonide
elemental diet (esp if not wanting to use steroids eg young kids)
5ASA (mesalazine) - 2nd line but not as good as steroids
azothiaprine, methotrexate, mercaptopurine - useful as add on but not monotherapy for inducing remission
Infliximab for refractory or fistulating disease
metronidazole for isolated peri-anal disease

''Maintenance''
Stop smoking - most useful intervention (Note in UC smoking suppresses Sx)
azothiaprine or mercaptopurine 1st, methotrexate 2nd,
5ASA if previous surgery

Note 80% of crohns will eventually need surgery
Pre Aziothioprine or mercaptopurine need to assess TPMT (thiopurine methyltransferase) activity