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afya Breast Cancer Mx

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20160425222447 Ben  
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Depends on stage, tumour type and pt background

''Surgery''
Offered to most pts (not frail elderly with mets)
WLE - solitary, peripheral, small lesion in large breast, DCIS <4cms
Mastectomy - multifocal, central, large lesion in small breast, DCIS >4cms
+/- reconstruction - immediate or delayed

''Radiotherapy''
recommended post WLE
post mastectomy if T3-T4 or 4+ LN

''Chemotherapy''
Pre or post surgery to downstage tumour or adjuvant

''Biologics''
Trastuzumab (Herceptin) - only for HER2 positive - cannot be used if Hx of heart disease

''Hormonal''
Offered if hormone receptor positive
Tamoxifen if pre-men for 5 yrs post diagnosis ?longer - SE - endometrial ca, VTE, menopausal Sx
Aromatase inhibitors if post men (aromatisation leads to oestrogen production peripherally).