Don't prescribe unless no alternative - have phrases prepared to refuse or give at lowest dose for shortest time note why started and what problems caused manage withdrawal slowly, carefully and with other active coping mechanisms to schedule agreed with patient 2-3% adults in UK take regularly - more female and older, esp if in care home role in - acute arousal / anxiety / insomnia, alcohol withdrawal, epilepsy, anaesthesia not for chronic insomnia, epilepsy, spasticity, anxiety problem - as cause dependance, toxicity (synergistic with other drugs), abuse confusion and falls esp in elderly withdrawal - usually 3-7 days after stopping - agitation and insomnia general - tremor, twitches, nausea, palpitations, aches, headache (days) - insomnia, anxiety (weeks) - panic attacks, depressed, poor concentration, irritable serious - seizures, delirium, hallucinations, delusions, paranoia longer acting drugs - withdrawal is longer but less severe taper all drugs when withdrawing for successful withdrawal convert to longer acting drug and taper it manage anxiety and insomnia with non-drug means and info usually do at home (collect drug daily ??) but occ in hospital Dependance Physiological - develops tolerance and shows withdrawal Sx BZD dependance syndrome - cluster of cognitive, behavioural and physiological includes compulsion to use - drug seeking behaviour, usually with marked tolerance high risk - other substance abuse / maladaptive personality (impulsive, anxiety, dependant) if suspected - question pt - why do they want benzo / what happens if don't take / what other drugs used / how oftern do they take ?? consider withdrawal / toxicity ... other drugs abused (IV ??) Withdrawal Must be agreed by pt ask about pt experience of and feelings about drugs give plenty of info programme over months - reducing dose by 10% per week ? ?have formal signed contract