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afya Bendroflumethazide

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20160425222535 Ben  
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Inhibits sodium absorption at beginning of distal convoluted tubule
Potassium lost as more sodium reaches collecting duct
role in mild heart failure (but loop better) and was used in HT but Indapamide/Chlortalidone better
starts to act within 1-2hrs, duration 12-24 hrs
OK when breast feeding (small amts go through but too little to worry)

''SE - common''
dephydration  -  postural hypoT and impotence
hypo Na K 
hyper Ca glc (IGT)
gout

''SE rare'' (TAPP)
thrombocytopenia
agranulocytosis
photosensitivity rash
pancreatitis