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common skin disorder which usually occurs in adolescence. 
typically affects face, neck and upper trunk
characterised by obstruction of the pilosebaceous follicle with keratin plugs which results in comedones, inflammation and pustules.

classified ...
mild: open and closed comedones with or without sparse inflammatory lesions
moderate: widespread non-inflammatory lesions and numerous papules and pustules
severe: extensive inflammatory lesions, which may include nodules, pitting, and scarring

''Epidemiology''
    affects around 80-90% of teenagers, 60% of whom seek medical advice
may persist beyond adolescence, 10-15% of females and 5% of males over 25 years old being affected

''Four factors''
//Inflammation// - Benzoyl peroxide – 2.5% as good as 10% or antibiotics or oral retinoids
//proliferation of proprionibacterium acnes// – antibiotics or oral retinoids
//comedones// (abnormal keratin proliferation) – topical retinoids or oral retinoids
//Androgen driven sebum production// (though many with acne have normal androgen levels) – COCP or oral retinoids