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report adverse effects
Medicines and healthcare products regulatory agency

report
all adverse drug reactions in new drugs (black triangle in BNF)
all adverse drug reactions in paeds (including off label use)
all serious drug reactions for established medicines or vaccines including off label use, herbal remedies, unlicensed meds

serious - fatal, life-threatening, disabling, incapacitating, resulting in prolonged hospitalisation or medically significant

cards found in BNF or online (yellowcard.gov)
report suspect reactions not just confirmed ones
can be reported by patients
MHRA collates and assess cards who may then consult with Commission on Human Medicines - independent scientific body