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afya
Triglyceride
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> fat store - energy source, thermal insulation, adipocytes act as a mechanical cushion eg round kidneys 2ndary cause - alcohol, uncontrolled diabetes, drugs eg isotretinoin main worry is pancreatitis ''Ix'' - Urinalysis, fasting lipid and glc, LFT, U/E, TSH, creatine Kinase ''Aims ....'' fasting TG <1.7 (but any reduction dec risk of pancreatitis) If >10 ? refer to secondary care (>20 urgently unless poor glc control or xs alcohol is clearly cause) ''Mx '' lifestyle, esp alcohol and diabetes statin unless normal cholesterol or CI if still >5.6 after 3/12 then ... Omega-3 1-2g bd (unless unable to take fish) If still >5.6 consider ? refer ? for fibrate or nicotinic acid ''Causes of secondary ....'' |nephrotic syndrome|chol ++ |TG (+)|hypothyroidism|chol ++| TG +|biliary obstruction|chol+ |TG (+)| |pregnancy|chol +||myeloma|chol+||porphyria|chol +|| |steroids|chol+|TG +|obesity|chol +|TG +|diabetes mellitus|chol (+)|TG ++| |renal failure||TG +|excess ethanol intake||TG ++|beta blockers||TG +| |thiazide diuretics|chol +|TG +|isotretinoin||TG+|oral contraceptive pill||TG+| |lipodystrophies||TG+|glycogen storage disease||TG+||||
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LipidsAndStatins