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SteroidS
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> |Mineralocorticoid|Drug|Glucocorticoid| |Very high|Fludrocortisone|Minimal| |High|Hydrocortisone|Some| |Low|Prednisolone|Predominant| |Minimal|Dexamethasone|Very high| ''Side effects'' - greatest limitation to use //Gluco ..// (PIG ICE MOG) Psychiatric - insomnia, mania, depression, psychosis (DIMP) Immunosuppression - infection risk, TB reactivation GI - peptic ulcer, pancreatitis intracranial HT Cushings - moon face, buffalo hump, striae endocrine - imparied glc regulation, wt gain/inc appetite, hisutism, hyperlipid Musculoskeletal - osteoporosis, proximal myopathy, avascular necrosis - femoral head Ophthalmic - glaucoma, cataracts growth in children suppressed //Mineralo ...// Fluid retention HT Double dose in intercurrent illness gradual withdrawal if >40mgPred >1/52 or >3/52 Rx or repeated courses
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