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Raynaud'sPhenomena
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<<forEachTiddler where 'tiddler.tags.contains(context.inTiddler.title)' sortBy tiddler.title ascending write '"*[["+tiddler.title+"]]\n"'>> <<tiddler AutoRefresh with: force>> primary or secondary ''Raynaud's disease'' (primary) young women (30y) with symmetrical attacks Factors suggesting underlying connective tissue disease onset after 40 years unilateral symptoms rashes presence of autoantibodies features which may suggest rheumatoid arthritis or SLE, for example arthritis or recurrent miscarriages digital ulcers, calcinosis very rarely: chilblains ''Secondary causes'' connective tissue disorders: scleroderma (most common), rheumatoid arthritis, SLE leukaemia type I cryoglobulinaemia, cold agglutinins use of vibrating tools drugs: oral contraceptive pill, ergot cervical rib ''Management'' first-line: calcium channel blockers e.g. nifedipine IV prostacyclin infusions: effects may last several weeks/months
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Dermatology