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ProstheticHeartValves
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> most common valves to replace - aortic and mitral either biological (bioprosthetic) or mechanical. ''Biological (bioprosthetic) valves'' Usually bovine or porcine in origin Major disadvantage - structural deterioration and calcification over time. older patients ( > 65y aortic, > 70y mitral) receive a bioprosthetic valve Long-term anticoagulation not usually needed. Warfarin for first 3/12 then Low-dose aspirin ''Mechanical valves'' most common - bileaflet valve. Ball-and-cage valves are rarely used nowadays Mechanical valves have a low failure rate Major disadvantage - increased risk of thrombosis meaning long-term anticoagulation Aspirin as well unless contraindication. Target INR - aortic: 2.0-3.0, mitral: 2.5-3.5 2008 NICE guidelines for prophylaxis of endocarditis - antibiotics not needed for common procedures eg dental
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Cardiovascular