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afya
ManageAsthma
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> primary prophyllaxis breast feeding mixed smoking - exacerbates but doesn't cause avoid allergens, irritants - no evidense Stop smoking - cigarettes dec effectiveness of treatment, in airway hyper responsiveness and cause other lung disease NICE/SIGN 11 statements '' 5 steps'' 1 inhaled SABA prn 2 inhaled steroid 400 /day (200-800) 3 LABA then inc steroid to 800 4 steroid at 2000 or montelukast or theophylline 5 oral steroid / 2ndary care '' Leukotriene receptor antagonists'' anti-inflammatory and bronchodilator use when poorly controlled on high dose inhaled steroids and LABA useful in aspirin induced associated with Churg Strauss Fluticasone more lipophilic so longer acting that beclometasone Chloroflurocarbon propellant is being replaced with hydrofluoroalkane which is smaller so half previous dose LABA - bronchodilator and inhibits mediator release from mast cell - improves Sx more than doubling steroid dose
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