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Infectious mononucleosis
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> also called glandular fever caused by Epstein-Barr virus (human herpesvirus 4) common in adolescents and young adults. ''Features'' sore throat lymphadenopathy pyrexia malaise, anorexia, headache palatal petechiae splenomegaly - occurs in around 50% of patients and may rarely predispose to splenic rupture hepatitis presence of 50% lymphocytes with at least 10% atypical lymphocytes haemolytic anaemia secondary to cold agglutins (IgM) a maculopapular, pruritic rash develops in around 99% of patients who take ampicillin/amoxicillin whilst they have infectious mononucleosis ''Diagnosis'' heterophil antibody test (Monospot test) ''Management'' - supportive rest during the early stages, drink plenty of fluid, avoid alcohol simple analgesia for any aches or pains consensus guidance in the UK is to avoid playing contact sports for 8 weeks after having glandular fever to reduce the risk of splenic rupture
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