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afya
GuillainBarre
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> immune mediated demyelination of the peripheral nervous system often triggered by an infection (classically Campylobacter jejuni). The characteristic features of Guillain-Barre syndrome is progressive weakness of all four limbs. The weakness is classically ascending i.e. the lower extremities are affected first, however it tends to affect proximal muscles earlier than the distal ones. Sensory symptoms tend to be mild (e.g. distal paraesthesia) with very few sensory signs. Some patients experience back pain in the initial stages of the illness Other features areflexia cranial nerve involvement e.g. diplopia autonomic involvement: e.g. urinary retention Less common findings papilloedema: thought to be secondary to reduced CSF resorption
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Neurology