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Cleft Lip and Palate
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> 1 in every 1,000 babies. ''Pathophysiology'' polygenic inheritance maternal antiepileptic use increases risk cleft lip results from failure of the fronto-nasal and maxillary processes to fuse cleft palate results from failure of the palatine processes and the nasal septum to fuse ''Problems'' feeding: orthodontic devices may be helpful speech: with speech therapy 75% of children develop normal speech increased risk of otitis media for cleft palate babies ''Management'' cleft lip is repaired earlier than cleft palate, with practices varying from repair in the first week of life to three months cleft palates are typically repaired between 6-12 months of age
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