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Atypical anti-psychotics
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<<forEachTiddler where 'tiddler.tags.contains(context.inTiddler.title)' sortBy tiddler.title ascending write '"*[["+tiddler.title+"]]\n"'>> <<tiddler AutoRefresh with: force>> first-line in schizophrenia, (2005 NICE) main advantage - reduction in extra-pyramidal side-effects. ''Adverse effects'' weight gain clozapine (agranulocytosis (1%) - need regular FBC, so only 2nd line, neutropenia (3%), reduce seizure threshold (3%)) Warning in elderly (MHRA) increased risk of stroke (especially olanzapine and risperidone) increased risk of venous thromboembolism ''Examples'' clozapine olanzapine risperidone quetiapine amisulpride
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Psychiatry