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afya
ACEinhibitors
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<<forEachTiddler where 'tiddler.tags.contains(context.inTiddler.title)' sortBy tiddler.title ascending write '"*[["+tiddler.title+"]]\n"'>> <<tiddler AutoRefresh with: force>> Used for younger HT (not so good in afro-carribeans) in heart failure, diabetic nephropathy and 2ndary prevent IHD inhibit conversion of angiotensin 1 to 2 ''SE'' (ACEi (E becomes H)) Angioedema (up to 1 yr) Cough - 15% for up to 1yr (?due to bradykinin increase) Hypotension esp if also on diuretics (loop) or AS (Ist dose) Inc K - Hyperkalaemia ''Cautions / CI'' Avoid in pregnancy and breast feeding renal impairment if bilateral renal artery stenosis aortic stenosis (causes hypotension) high dose diuretic (fruse 80) inc risk hypotension herediatary idiopathic angioedema ''Monitour'' U/E - at start and if inc dose rise of 30% from baseline creatinine (25% fall in eGFR) and up to 5.5 K are acceptable - NICE
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Cardiovascular, CVSdrugs